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Re: DewDiligence post# 167607

Sunday, 10/06/2013 2:32:01 PM

Sunday, October 06, 2013 2:32:01 PM

Post# of 257262

ABBV/ENTA—Do you concur with the SAPHIRE-1/2 expectations in #msg-92714916?





Your target numbers are in-line with my own expectations. Treatment-experienced patients in SAPHIRE-2 (SVR12>=90%) may be the tougher nut to crack. A couple of questions



1- Has ABBV disclosed the GT1A to GT1B patient ratio in SAPHIRE-1/2?

2- Are any of the treatment-experienced patients in SAPHIRE-2 P.I. failures?


The PEARL studies (without ribavirin) will be more difficult to call, and of greater future importance IMO.

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