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Re: Sooah post# 80265

Sunday, 06/23/2013 11:33:47 PM

Sunday, June 23, 2013 11:33:47 PM

Post# of 158400
One cannot start the trial with a large group directly. Clinical trials are done in multiple phases.

phase I Testing of drug on healthy volunteers for dose-ranging often subtherapeutic, but with ascending doses clinical researcher 20-100 determines whether drug is safe to check for efficacy
They need to determine the dose first and determine its efficacy and then sybaequently increase the I've of the group.

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