Amarin Corp Plc (AMRN)

[mtds]

Inflammation is key reason for successful JELIS study in Japan.Dr.Barry Sears sent me an article from Athero. and Thrombosis Journal published in 2011 by Japanese using JELIS data.It showed Inflammation as measured by AA/EPA ratio. For subgroup of people ,This ratio -EPA/AA dropped from 1.6 to 0.8.
Another article in 2012 using Jelis data showed that DHA is correlated with LDL ,but EPA is not.
Recently Dr.Topol --wrote an Op.ED article about harmful effects of Statins--causing Type 2 diabeties.He felt that high dose of Lipitor,Crestor or Zocor is the cause.He is not rejecting Statins--but feels that caution is required and new approach to reducing LDL,C-RP needs to be looked at.
There ia another product is being developed-but it won't be approved until 2015 or 2016.
Vascepa--is a drug--that reduces trigylcerides and C-RP. Dr.Sears told me that 6 grams/day of EPA would reduce cardiac events based on his research.
You are right--many cardiologists need confirmation from Reduce-It study to prescribe it in large numbers.
Anchor study -in the meantime-is compelling information. Recently--Dr.Sinatra appeared on Dr.OZ show--he is against Statins.He uses TG/HDL ratio as that is convincing to him with definitive studies.
VASCEPA reduces TG and C-RP and AA/EPA ratio--all inflammation indicators.