JNJ/AGN/VRX—Clinical studies in this area are notorously bogus, because it is difficult (close to impossible) to tell or define other than in a subjective way, when the [botulinum toxin] stops working.
Comparisons between arms can be done with blinded assessments by the patient and the investigator.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”