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Re: tborges post# 11938

Tuesday, 01/15/2013 5:11:39 PM

Tuesday, January 15, 2013 5:11:39 PM

Post# of 12383
May I suggest Gendicine & ENMD 2076 combo


"The recent publication of preclinical results for ENMD 2076 in TNBC cancer lines revealed that activity was greater in those cell lines with increased P53 expression."

"http://www.entremed.com/news/entremed-announces-publication-of-preclinical-results-for-enmd-2076-in-triple-negative-breast-cancer/";

Tborges, building on your idea of improving ENMD 2076 effectiveness I would like to suggest the Gendicine & ENMD 2076 combo. As you noted, ENMD 2076 was more effective in cancer cell lines with increased p53 suppresser genes expression. Then why not use Gendicine (a p53 gene therapy treatment) to improve the outcome of ENMD 2076.


I found Gendicine on a China cancer therapy site. It's a gene therapy that introduces p53 genes into cancer via a virus. It's also only done in China.

http://www.cancertherapychina.com/index.php?option=com_content&view=article&id=84&Itemid=23

Aaron

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