Avid Bioservices Inc (CDMO)

[Protector]

It is only now that the word 'certainly' in the sentence below comes to my attention.

Even though we haven't reached MOS, and certainly may not have reached it by then,

Now I am going to make a jump here! Assume the word 'certainly' was used knowledgeably and it's not just there in the phrase as a filler. So then 'certainly' means 'certainly', does it!

What knowledge about the clinical trial would one need to have to be able to claim that MOS may 'CERTAINLY' (not maybe or possibly) NOT be reached at the 7th September Chicago presentation?

From what I understand from all the CT stuff, and that's nothing compared to what some of the specialized posters on this board know about it, i would say :

1) You must be sure that 50% of your Bavi arms patients are still alive on 7th September to be certain.
2) You can only be sure of that if you are sure that at least 50% of your Bavi patients didn't die by 7th September of CT related causes.
3) You can only be sure of that if at least 50% of the patients either have a Complete Response (CR) or are Progression Free and in a good condition the live on.

I cannot envisage another situation in which 'certain' can really mean 'certain' because unless a patient had complete response or is progression free one can't guarantee that patient will not die before the 7th of Sept from a Clinical Trial related cause.

Any other reason for the usage of the word "certain" can only be found in the assumption that the number of survivals is so high and their condition so good that a high probability has been translated into "certainty".

In both cases we are good!