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Re: oc631 post# 146297

Friday, 08/03/2012 10:50:17 PM

Friday, August 03, 2012 10:50:17 PM

Post# of 257275

ALS-2220 is a purine nuke so safety is an ongoing concern. Positive efficacy data from the pyrimidine ALS-2158 would be exciting for VRTX.

Thanks oc, I missed this point. This further strengthens my belief that VRTX will ultimately need a 2nd gen PI or NS5A inhibitor to compete effectively in the HCV space down the road.

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