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oc631

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oc631

Re: DewDiligence post# 146290

Monday, 07/30/2012 11:20:24 PM

Monday, July 30, 2012 11:20:24 PM

Post# of 257275


VRTX reports 7-day monotherapy data on ALS-2220, one of the two HCV nukes licensed from Alios BioPharma in 2011





ALS-2220 is a purine nuke so safety is an ongoing concern. Positive efficacy data from the pyrimidine ALS-2158 would be exciting for VRTX. Suggesting they will partner the drug with Incivek (in GT1) unfortunately will make it hard to take their HCV program seriously.
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