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Re: mcbio post# 145976

Tuesday, 07/24/2012 7:14:32 PM

Tuesday, July 24, 2012 7:14:32 PM

Post# of 257266
What are the RDEA594 contraindicated but not BCRX4208 contraindicated? I don't see anything meaningful. Actually it might be the other way around, more BCRX contraindicated than RDEA594 contraindicated.

As of RDEA594 failure, first of all, it is a very small population; second, they'll need to run a trial on that population. Who knows if the drug works in that population regardless of MOA.

It is tough to be behind a drug with both superior efficacy and better safety profile, as well as development timeline.

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