Very interesting indeed - wonder if that is a class effect or peculiar to this compound. If it's a class effect that would be very bad.
There is a BB company Diadexus (based on IP from INCY I think) that sells a test for LP-pla2.
When I looked at Diadexus a couple of years ago, the LP-pla2 angle looked pretty convincing to me. Never invested though and haven't followed them at all. If I recall correctly, they were pinning their hopes on a large GSK trial of a drug that aimed to reduce LP-pla2 - not sure if the trial has reported yet or not.