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Re: jessellivermore post# 141483

Monday, 05/07/2012 6:34:19 PM

Monday, May 07, 2012 6:34:19 PM

Post# of 257648

reported rise in LP-pla2 in the Roche trial



Very interesting indeed - wonder if that is a class effect or peculiar to this compound. If it's a class effect that would be very bad.

There is a BB company Diadexus (based on IP from INCY I think) that sells a test for LP-pla2.

When I looked at Diadexus a couple of years ago, the LP-pla2 angle looked pretty convincing to me. Never invested though and haven't followed them at all. If I recall correctly, they were pinning their hopes on a large GSK trial of a drug that aimed to reduce LP-pla2 - not sure if the trial has reported yet or not.

http://www.diadexus.com/

Peter



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