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Re: DewDiligence post# 135743

Tuesday, 02/14/2012 9:20:55 AM

Tuesday, February 14, 2012 9:20:55 AM

Post# of 251954
BIIB acquires Stromedix (private) for $75M up-front and $488M in contingencies:

http://finance.yahoo.com/news/Biogen-Idec-Acquire-Stromedix-bw-1248246961.html?x=0

Stromedix’s lead candidate, STX-100, is a novel humanized monoclonal antibody that selectively disrupts the TGF-beta pathway, which plays a central role in fibrotic disease. STX-100 exhibited significant anti-fibrotic activity in preclinical animal models of fibrotic disease and demonstrated an attractive safety and tolerability profile in a Phase 1 trial. Stromedix has also identified a series of clinical biomarkers that reflects the biological activity of STX-100. STX-100 is entering a Phase 2 trial in patients with idiopathic pulmonary fibrosis (IPF), a debilitating and almost uniformly fatal disease in which patients experience progressive difficulty breathing due to fibrosis (scarring) of the lung.


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