Biotech Values

[exwannabe]

CLDX: mcbio, 011 P2 trial ?

I have a bit of shares there, but am beginning to worry about the odds of the 011 trial data being good (i.e. stat sig ORR).

The trial is N=120, randomized 2-1

I would presume the control arm (investigator's choice) can hit 5% or so, 1 or 2 ORs.

In the earlier trial the ORR in GPNMB+ was unknown because not all patients were tested (why?). But it can be estimated to be in the low teens.

Those numbers projected onto this trial will not do well.

Do you think 011 has good a good chance in this trial? And if so, why?

Thanks.