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Re: NP1986 post# 127232

Friday, 09/23/2011 4:58:50 PM

Friday, September 23, 2011 4:58:50 PM

Post# of 257307

The question in my mind is what else, if anything, does '113 block at nanomolar concentrations?



Not yet disclosed as far as I know. They do say it shows significant selectivity over insulin-like growth factor-1 receptor and insulin receptor tyrosine kinases. That's important because they have very similar structures to ALK.

The July lung cancer conference poster on '113 is available:

http://phx.corporate-ir.net/External.File?item=UGFyZW50SUQ9NDMxODc1fENoaWxkSUQ9NDUwMDAwfFR5cGU9MQ==&t=

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