Biotech Values

[NP1986]

I'm interested to learn more about their magical block everything in the world pill.

Well, as far as we know it's only ALK and activated EGFR that it blocks. It does seem rather serendipitous that it blocks two pathways that have been implicated in non-small cell lung cancer, but lest we forget, so does crizotinib (c-MET and ALK). The question in my mind is what else, if anything, does '113 block at nanomolar concentrations? I think once the preliminary safety data are out, and if there are no worrying off-target effects, then I will be quite confident about the prospects of this drug.