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Re: mcbio post# 126129

Sunday, 09/04/2011 1:46:38 PM

Sunday, September 04, 2011 1:46:38 PM

Post# of 257426

Interesting. So, they are dropping [GS 9190] from these trials, which also includes one of their PIs (GS 9451 or GS 9256), pegylated interferon, and ribavirin.




The P.I.'s appear to be getting a clean bill because single SAE's were experienced in separate studies which is understandable in hindsight. If GS9190 is responsible for the SAE's (which I feel is more than likely) GILD may setback their protease inhibitor development program if SAE's reappear again in oral combo studies.

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