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Re: biomaven0 post# 123995

Wednesday, 07/27/2011 10:17:10 PM

Wednesday, July 27, 2011 10:17:10 PM

Post# of 252444

It's all very puzzling. With the gamma secretase news, maybe amyloid as a protective response is starting to look more plausible. I guess that would leave tau as the next batter up.

What about the beta secretase inhibitors? What's the latest on them? I know LGND has one in Phase 1 partnered with MRK via their prior acquisition of Pharmacopeia. I take it the point of them is still to try to prevent amyloid production and overall point being that this may not be the best approach.

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