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Re: DewDiligence post# 123139

Sunday, 07/10/2011 2:54:51 PM

Sunday, July 10, 2011 2:54:51 PM

Post# of 257257
If one knew the total percentage of prefilled enoxaparin scripts for each dosage available, one could determine the amount of scripts used for prophylaxis of DVT versus treatment of acute DVT, PE and "bridge therapy". Essentially 100% of all 30mg and 40mg dose fills would be for prophylaxis, and 100% of all other dosages would be used for treatment of acute DVT or PE or bridge therapy.

I would estimate 6-10% of outpatient enoxaparin prescriptions are used to treat DVT as an outpatient. A patient may have a one day observational stay, or simply an ER visit, instructed on home use of enoxaparin at 1mg/kg twice daily, sent home and simultaneously started on warfarin. These people typically require 5-7 days of enoxaparin until therapeutically anticoagulated with warfarin.

Enoxaparin is also used in the hospital and for outpatient treatment of pregnant women with DVT/PE or who typically require longterm warfarin use. [not a big market, but it certainly exists]

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