Which metal? Aluminum or zinc? Yes, zinc finger proteins help turn genes on or off. As to whether iron transport could be a causal factor, I wasn't aware of that. Thank you for the link.
"early-onset AD"
Given that has a 50:50 chance of being inherited, and is EARLY ONSET (i.e., before age 50), is it really the same disease? It's well researched, so obvious links should be known by now if it was simple.