Biotech Values

[iwfal]

HCV - Update to all orals programs:

VRTX Telaprevir VX-222 non-nuke some BID clinicaltrials.gov/ct2/show/NCT01080222

SVR trial in treatment naive - RIP - Killed for breakthroughs
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Roche ITMN-191 RG7128 nuke none TID/BID clinicaltrials.gov/ct2/show/NCT00801255

INFORM 1 - 14 day trial (in all comers) - Results:

http://investor.pharmasset.com/releasedetail.cfm?ReleaseID=421306
.
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BMY BMS-650032 BMS-790052 NS5A some BID clinicaltrials.gov/ct2/show/NCT01012895

SVR Trial in G1 Nulls - Interim results >50% breakthroughs thru SVR12. Results:

http://www1.easl.eu/easl2011/program/Orals/429.htm
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GILD GS9256 GS9190 non-nuke some BID clinicaltrials.gov/ct2/show/NCT01072695

Treatment naive, 28 day response (followed up by SOC) - inadequate viral efficacy

http://investorshub.advfn.com/boards/read_msg.aspx?message_id=52470566
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B-I BI 201335 BI 207127 non-nuke all TID/BID clinicaltrials.gov/ct2/show/NCT01132313

Treatment naive dose ranging with Rib for 24 or 48 weeks. Not scheduled to finish until 2014.
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IDIX IDX320 IDX184 nuke TBD qD

On hold (or killed) due to tox.

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NEW TRIALS initiated more recently:

VRUS 7977/938 Ph 1 trial 14 day trial - results http://www1.easl.eu/easl2011/program/Posters/Abstract8.htm

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RO5024048 (aka RG7128) And Danoprevir (aka ITMN-191)
Treatment naive G1 - 12 or 24 weeks +/- Rib - results due in 2012
http://clinicaltrials.gov/ct2/show/NCT01278134?term=RO5024048+danoprevir&rank=1

Any others I am missing?