Biotech Values

[DewDiligence]

Who’s Who in All-Oral HCV Programs

[New table format includes columns for dosing frequency, use
of ribavirin, and links to clinicaltrials.gov; added B-I program.]

 
          Protease     Other      Non-PI    Arms w     Dosing 
 Company  Inhibitor   Compound    Class    Ribavirin  Frequency  Link 
 VRTX     Telaprevir  VX-222     non-nuke    some       BID      http://clinicaltrials.gov/ct2/show/NCT01080222 
 Roche    ITMN-191    RG7128       nuke      none      TID/BID   http://clinicaltrials.gov/ct2/show/NCT00801255 
 BMY      BMS-650032  BMS-790052   NS5A      some       BID      http://clinicaltrials.gov/ct2/show/NCT01012895 
 GILD     GS9256      GS9190     non-nuke    some       BID      http://clinicaltrials.gov/ct2/show/NCT01072695 
 B-I      BI 201335   BI 207127  non-nuke    all       TID/BID   http://clinicaltrials.gov/ct2/show/NCT01132313 
 IDIX     IDX320      IDX184       nuke      TBD         qD      *

*Drug-drug-interaction study expected to start Jul/Aug 2010.