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Re: Biowatch post# 109638

Tuesday, 11/30/2010 5:19:36 PM

Tuesday, November 30, 2010 5:19:36 PM

Post# of 257269
I doubt there is ONE uniform disease biomarker for each disease you listed. It's much more complicated than that. The best you can hope for is to find certain biomarker that is related to the targeted treatment, which in turn to predict whether the patient will likely respond to the targeted treatment or not.

For example, there is genetic marker BRCA gene mutation for breast and ovarian cancer. People with BRCA gene mutation have increased RISK of developing breast/ovarian cancer. However, it doesn't mean you DEFINITELY develop breast/ovarian cancer if you have BRCA gene mutation. People who don't have BRCA gene mutation do develop breat/ovarian cancer. This illustrates the point it is much more complicated than genetic marker alone - there are other factors involved, both known and unknown.

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