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Re: iwfal post# 109605

Monday, 11/29/2010 8:04:51 PM

Monday, November 29, 2010 8:04:51 PM

Post# of 257302

But not good for final approval - at least not without additional data.



In prostate cancer that has metathesized "evidence of bone scan resolution (partial or complete)" occurred in 19 out of 20 patients treated with XL184. Bone/skeletal failure reductions should extend life, IMO since that is the main cause of death.

12 out of 20 had reduced pain.

Is that NOT good enough for approval?

smile

ij

There are times when rules and precedents cannot be broken; others when they cannot be adhered to with safety. (Thomas Joplin)

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