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Re: DewDiligence post# 109153

Thursday, 11/18/2010 6:40:10 PM

Thursday, November 18, 2010 6:40:10 PM

Post# of 257257
Re: NVS' DEB025

I assume the expectation is that DEB025 would ultimately be used as part of an HCV cocktail and not as a monotherapy +/- SoC. Assuming three HCV classes will be the norm for a future HCV cocktail, what class is the most susceptible to being replaced by a cyclophilin inhibitor? PI? Nuke? NS5A inhibitor? Just trying to understand where this different class could fit into the equation of an HCV DAA combo.

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