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Re: iwfal post# 106680

Wednesday, 10/20/2010 2:22:41 PM

Wednesday, October 20, 2010 2:22:41 PM

Post# of 257580
Re: All-oral HCV cocktails

Is there any value of SVR in the T+VX222 trial (in G1 naive patients) below which you would start to question the chances of a 3 drug DAA (wo SOC) taking over 90% of the market? <20%? <10%?

No, there isn’t. Because the Telaprevir + VX-222 cocktail does not contain a nuke, I would not unduly question the all-oral approach even if the trial in question were to produce an SVR rate of 0%.

I’d be interested in your own answer to the question you posed above (and in the answer of anyone else who cares to opine).

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