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Re: udrunkenmonkey post# 96776

Sunday, 06/06/2010 6:15:35 AM

Sunday, June 06, 2010 6:15:35 AM

Post# of 257253
BMY/Ipilimumab:

The survival benefits are certainly a step in the right direction, but 4 months may be a hard sell to patients given the possible adverse events.

As you probably know, the median values per se don’t mean squat. I haven’t seen the Kaplan-Meier curves for the Ipilimumab arms vs the (gp100) control arm, but it’s clear from the one-year and two-year survival rates reported in #msg-50952301 that a large portion of the survival benefit is attributable to the rightmost tail. This is hardly surprising given Ipilimumab’s immune-boosting MoA (#msg-50952010 bottom). Regards, Dew

p.s. Please see the photos in #msg-47415590 if you have not already done so.


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