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Re: floblu14 post# 93917

Sunday, 04/11/2010 6:31:25 PM

Sunday, April 11, 2010 6:31:25 PM

Post# of 251721
M118 EMINENCE Study Met Prespecified NI Threshold



The above table from the paper in the Apr 2010 issue of Circulation
(#msg-48705801) shows the prespecified non-inferiority analysis.

The criterion for a finding of non-inferiority was that the upper bound
of the 90% confidence interval on the primary endpoint delta of M118
relative to unfractionated heparin (UFH) was less than 0.08 (i.e. 8.0
percentage points). This criterion was met by each individual
M118 arm and by the composite of the three M118 arms.


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