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Re: mcbio post# 86274

Saturday, 11/14/2009 12:12:32 AM

Saturday, November 14, 2009 12:12:32 AM

Post# of 257257
Note there was a failed Phase III trial of a protamine alternative some years back with a compound (Heparinase-I) that cleaved heparin. The presumed reason for failure is that the cleaved heparin acted like a LMWH, although for the life of me I don't know why that wouldn't have shown up in earlier trials.

Peter

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