"Geno-2/3 patients have been harder to cure than geno-1/4 patients for any drug regimen I know of that’s been tried against all of the HCV genotypes."
i think you have that backwards - gen2/3 do better than 1/4, and typically require shorter treatment periods (soc is 24 weeks for gen2/3, and may be even shorter than that depending on viral kinetics)