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Re: iwfal post# 86233

Friday, 11/13/2009 4:19:10 PM

Friday, November 13, 2009 4:19:10 PM

Post# of 257580

why would genotype 2/3s still be treated 48 weeks once their is a direct anti-viral on the market? Unless you are referring to the fact that the G2/3 trials are lagging?

Geno-2/3 patients have been harder to cure than geno-1/4 patients for any drug regimen I know of that’s been tried against all of the HCV genotypes. Moreover, among the three main classes of direct antivirals, only the nukes offer pan-genotypic coverage; by and large, the non-nukes and protease inhibitors in development today have been tailored for genotype 1.


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