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Re: DewDiligence post# 85426

Tuesday, 10/27/2009 6:55:44 PM

Tuesday, October 27, 2009 6:55:44 PM

Post# of 257262
Re: VX-813/VX-985

It’s reasonable to infer that the second-gen protease inhibitors, VX-813 and VX-985 are effectively dead.

Why would VRTX drop the second-gen PIs? Is VRTX just naive and thinking that telaprevir can't be improved upon to a much greater degree or, what I assume, does VRTX just not believe that these two compounds do not improve upon telaprevir enough coupled with the fact that they're so far behind?

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