Biotech Values

[DewDiligence]

This could be a well-contoured IPO:

[Privately-held Thermage has perhaps the best treatment available to turn back the clock without surgery. If they IPO, I will give it serious consideration. Makers of dermal fillers using collagen and hyaluronic acid should be concerned.]

http://biz.yahoo.com/prnews/040823/nym055_1.html

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Thermage(R) Big Fast Treatment Tip Makes A Big Difference in Tissue Tightening and Contouring

HAYWARD, Calif., Aug. 23 /PRNewswire/ -- Thermage® is pleased to announce the immediate availability of the new Big Fast 1.5 ThermaTip(TM) device. The larger size 1.5 treatment tip treats 50% more surface area with each firing, enabling efficient implementation of the current multiple-pass treatment guidelines. With comparable efficacy to the current standard tip, physicians and patients can achieve tissue tightening and contouring effects in a shorter period of time.

Key benefits of the Big Fast Tip include:

* Larger volume of collagen affected with each firing.

* Equivalent efficacious treatment depth as the 1.0 Fast Tip and

Standard Tip

* Sophisticated tip-to-skin detection for safe RF delivery

* Increased "firings" -- up to 450 per tip totaling 675 square

centimeters of coverage

* Reduced overall treatment time per patient

The recent availability of the Big Fast 1.5 provides physicians the key tool for effective and efficient implementation of current treatment guidelines. In recognition of this and their commitment to their customers, Thermage offered all ThermaCool(TM) users the ability to trade-in previously purchased tips towards the purchase of the Big Fast. In addition, the launch program included an instructional DVD for physicians on techniques to optimize skin tightening and contouring effects using the Big Fast treatment tip.

According to leading plastic surgeon Dr. Charles Hughes, the Big Fast 1.5 treatment tip adds predictability to this unique non-invasive radiofrequency- based skin tightening and contouring treatment. "Patients treated with the Big Fast tips are more comfortable, and I find that it speeds the procedure time without compromising the clinical outcome. In fact, we're achieving a more consistent response with equivalent more noticeable results in less time, making the entire treatment a more satisfying experience for our patients," said Dr. Hughes of Indianapolis, Indiana.

Dr. Roy Geronemus, renowned dermatologic surgeon and director of the Laser & Skin Surgery Center of New York, commented, "I have converted 100% of my Thermage procedures to usage with the new 1.5 tip because I believe it produces a more predictable clinical effect."

The Thermage patented capacitive radiofrequency (RF) technology deploys deep, uniform and volumetric heating to tighten and contour both skin and underlying tissue, while protecting the skin's outer layer with a cooling cryogen spray. The deep heating action promotes immediate collagen contraction beneath the skin surface and generates new collagen growth over time.

About Thermage

Thermage is a leading medical device company that develops innovative aesthetic technologies, including its patented capacitive radiofrequency device, to achieve a desired cosmetic or therapeutic effect on and under the skin surface. The ThermaCool System is currently installed in more than 1,000 dermatology, plastic surgery and other cosmetic surgery practices worldwide. Founded in 1996, the Company's headquarters are located in Hayward, California, proximate to the San Francisco Bay Area and the Silicon Valley. For more information about Thermage and its ThermaCool system, or to locate physicians using its exclusive radiofrequency technology, log on to http://www.thermage.com.
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