I spend my "gaming" money on Vegas and lottery tix. Of course, I would never, nor would I recommend anyone invest any money (and I do mean invest, not gamble/speculate) that they couldn't afford to lose.
It's not about risk, it's about risk/reward. It's only my opinion, but roughly this is how I look at it.
Skins has a 95% chance of dropping significantly (50% or more) and a 1% chance of going up 10 fold before any proven success. That means my expected value is about 60 cents on the dollar.
In this market, I have my choice of many companies with an even greater chance of a 10 fold or more increase, with far less risk, or many with a good chance of doubling with almost no risk of losing it all. Why would I want to invest in Skins no matter how little I needed the money?
I don't see it as risk tolerance (though anyone without a HUGE amount of risk tolerance shouldn't even be looking at OTC stocks), but simply smart investing.
Of course that's all simply my opinion, you are welcome to invest/speculate/gamble however you see fit.
'Tis better to be silent and be thought a fool, than to speak and remove all doubt. - Abraham Lincoln