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Re: gym gravity post# 76444

Thursday, 04/23/2009 12:21:32 PM

Thursday, April 23, 2009 12:21:32 PM

Post# of 257257
Oral HCV cocktail:

My guestimate is a little less then rkrw's with the caveat that it will likely be improved upon. As Thomas has pointed out INFORM results could give us a good hint at that. I would think Ribavirin may be around in the first go-round of an all oral regimen (in at least the non-responders).

Now if we say it happens in 4-6 years and even if you one assumes VRTX is one of the companies (but not the only; obviously I hope Roche/ITMN/VRUS is one) then one has to question the valuation for Vertex. Yes if they are alone perhaps even a higher valuation is warranted. But my opinion is that Telaprevir is far from the ideal Polymerase in this type of scenario especially if one believes (like I do) that treatment duration will be longer then that being investigated in the combos with PEG/Riba (I would guess 24 weeks and maybe even longer for an all oral regimen).

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