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Re: DewDiligence post# 76288

Tuesday, 04/21/2009 11:58:28 AM

Tuesday, April 21, 2009 11:58:28 AM

Post# of 257566
point well taken. I too am skeptical whenever MOA of drugs are not clear, and was also dubious in this case in particular since inhibiting polymerase, in and of itself, shouldn't have an effect on *existing* cccDNA based on the HBV life cycle. that said, there was curious data from the prior trial, and happy accidents have occurred in drug development

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