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Monday, April 20, 2009 7:55:19 PM
Caveat Emptor Re Nifty MoA Diagrams!
This is the diagram VRUS formerly employed to tout the
(allegedly) differentiated MoA of Clevudine compared to
other nucleoside polymerase inhibitors for HBV:
Well, that was the spin. What about the reality?
It’s unlikely, IMO, that Clevudine’s MoA was materially different from
Tyzeka’s MoA because Tyzeka and Clevudine are structurally as close
as two drugs could possibly be: Tyzeka (left), Clevudine (right).
This is the diagram VRUS formerly employed to tout the
(allegedly) differentiated MoA of Clevudine compared to
other nucleoside polymerase inhibitors for HBV:
Well, that was the spin. What about the reality?
It’s unlikely, IMO, that Clevudine’s MoA was materially different from
Tyzeka’s MoA because Tyzeka and Clevudine are structurally as close
as two drugs could possibly be: Tyzeka (left), Clevudine (right).
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