VRTX just started a second 3-day VCH-222 phase-1 monotherapy study in 32 treatment-naïve genotype-1 patients. VRTX’s CMO said on today’s CC that the previous 3-day VCH-222 study that VRTX touted as the main impetus for the ViroChem acquisition (#msg-36022752) contained only 5 patients!
Today’s CC made it crystal clear that VCH-222 is VRTX’s lead polymerase inhibitor; VCH-759, although further advanced than VCH-222, has been relegated to backup status and will be pursued only if VCH-222 falters.