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DewDiligence

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Re: mcbio post# 75270

Tuesday, 03/31/2009 9:32:56 AM

Tuesday, March 31, 2009 9:32:56 AM

Post# of 257253
Re: VRUS PSI-7851 / nucleoside vs nucleotide

I don't understand why the compound is first referred to as a nucleotide, but then under the "About PSI-7851" section, they call it a nucleoside.

The term nucleoside has two connotations: i) the structure shown in the left side of the graphic in #msg-34771363; and ii) a class consisting of both kinds of structures shown in #msg-34771363.

PSI-78512 is a nucleotide analog, as is IDX’s IDX184. The latter meaning of the term nucleoside (i.e. the structure class) is the one that VRUS is using in today’s PR.


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