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Re: mhigg post# 5711

Thursday, 04/17/2008 9:15:37 AM

Thursday, April 17, 2008 9:15:37 AM

Post# of 12660
And another stat question.

As I play around with a calculator, it seams that the final P value in OBF with a single interim peek will be around .48 with the interim at 50% of events and drop to around .4 as the interim gets out towards the 90% event time.

So, if the trial was always using OBF, how did pushing the interim back help the final alpha allocation? It should have hurt it.

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