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Re: genisi post# 60903

Tuesday, 04/01/2008 10:48:01 PM

Tuesday, April 01, 2008 10:48:01 PM

Post# of 257580
Re: Cordaptive

[This is a repost of a prior message with a typo correction in the last sentence.]

>They were titrating-up the Niaspan arm until week 12. Therefore, the Niaspan arm was only on 2gr for 4 weeks while the Cordaptive patients were exposed to 12 weeks.<

Is this really unfair? Isn’t part of the impetus for developing Cordaptive that its proprietary anti-flushing agent allows faster titration? Faster titration presumably means fewer office visits, less early medical intervention, and fewer discontinuations in a real-world setting.

In a long “outcomes” study, the difference in titration speed probably won’t matter much, however.

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