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Re: DewDiligence post# 60897

Tuesday, 04/01/2008 3:22:14 PM

Tuesday, April 01, 2008 3:22:14 PM

Post# of 257257
Just read this again:

>One group of patients received Cordaptive, beginning with 1-gram doses of the niacin component for the first month, and taking the full recommended 2-gram dose of niacin for the remaining 12 weeks of the study.

Another group took Niaspan, starting with 500 milligram doses of the extended release form of niacin and graduating to the recommended 2-gram dose by week twelve. They continued to take that dose for the remaining four weeks.<

They were titrating-up the Niaspan arm until week 12. Therefore, the Niaspan arm was only on 2gr for 4 weeks while the Cordaptive patients were exposed to 12 weeks.



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