>…the former [Tyzeka] is widely perceived to be an inferior agent in the marketplace…< Quite so; however, Recothrom is widely perceived to solve a problem that surgeons didn’t even know they had. >baraclude had pathetic us sales at launch (7M in its first 6 months!)< The way things appear to be going, you may need some luck to get to $7M of Recothrom sales in the same period.