Biotech Values

[DewDiligence]

MNTA’s Largest Shareholders

[Updated for today’s Form-13 filing from Visium.]

Below are the holdings of the largest shareholders
as of 12/31/07 and their holdings change (if known)
from 4/15/07 (the cutoff date for the 2007 annual-
meeting proxy). The equity stakes are as reported
to the SEC.

                       ---12/31/07--  Chng fm 
                        Shares  Stake  4/15/07 
 Novartis             4,708,679 13.0%    0.0 
 T Rowe Price         3,150,847  8.6%    n/a 
 Ziff Asset Mgmt      3,008,131  8.3%   -0.3* 
 Palo Alto Investors  3,102,460  8.5%   +2.4  
 Atlas/Peter Barrett  2,459,100  6.7%   -0.2* 
 Visium Asset Mgmt**  2,358,632  6.4%    n/a 
 Federated Investors  2,031,300  5.6%    n/a 
 Ridgeback Capital    1,768,592  4.8%    n/a 
 FMR                    566,800  1.6%   -7.9

*No change in shares; stake reduced slightly
due to increased no. of shares outstanding.

**Holding as of 3/5/08.

Orbimed Advisors, who was previously a 7.5% holder, filed a Form-13G on 11/7/07 showing they had sold out completely as of that date.

Polaris Ventures, who was a 5% holder in April 2007, no longer meets the 5% threshold needed to file Form-13G, evidently.