Atripla/Truvada from Gilead have all but locked up 2/3 of the market for first- and second-line HIV during the next 5-10 years. (The chart below is for the first line in US.)
orange: Atripla (Truvada+Sustiva) maroon: Truvada + something other than Sustiva green: Viread + two drugs other than Emtriva yellow: Three-drug cocktail excluding Viread
How can a company like IDIX hope to compete? One of the few chances is to supersede Sustiva as the NNRTI component of a 3-drug cocktail that includes Truvada. This is exactly what IDIX hopes to do with IDX899.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”