HCV: Most Likely to Succeed (IMHO)
In descending order of likelihood of success:
1. Telaprevir (VRTX/JNJ in phase-2).
2. The enhanced interferons: Albuferon (NVS/HGSI in phase-3) and Locteron (OctoPlus/Biolex in phase-2). I’m excluding Maxy-alpha from MAXY, which is now on hold, and ifn-lambda from ZGEN, which is an altogether different animal.
3. The “other” protease inhibitors: Boceprevir (SGP in phase-2) and ITMN-191 (Roche/ITMN in phase-1).
4. Various early-stage compounds from GILD (alone), GILD/ACHN, Roche/VRUS, Medivir/Tibotec, and IDIX.
JMHO, FWIW
“The efficient-market hypothesis may be
the foremost piece of B.S. ever promulgated
in any area of human knowledge!”