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Re: cjgaddy post# 52690

Saturday, 09/22/2007 3:54:08 PM

Saturday, September 22, 2007 3:54:08 PM

Post# of 257580
HCV: Most Likely to Succeed (IMHO)

In descending order of likelihood of success:

1. Telaprevir (VRTX/JNJ in phase-2).

2. The enhanced interferons: Albuferon (NVS/HGSI in phase-3) and Locteron (OctoPlus/Biolex in phase-2). I’m excluding Maxy-alpha from MAXY, which is now on hold, and ifn-lambda from ZGEN, which is an altogether different animal.

3. The “other” protease inhibitors: Boceprevir (SGP in phase-2) and ITMN-191 (Roche/ITMN in phase-1).

4. Various early-stage compounds from GILD (alone), GILD/ACHN, Roche/VRUS, Medivir/Tibotec, and IDIX.

JMHO, FWIW

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