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Re: palindromy post# 45118

Monday, 04/16/2007 12:37:05 AM

Monday, April 16, 2007 12:37:05 AM

Post# of 257432
Now, assuming(and I think it is a bad assumption) that 6/9 reflects true SVR20 proportion, the real SVR20 that would playout with larger study numbers could be assumed to be 0.666*0.799 = 0.532 ie 53.2%



You are still missing the drop-out effect however.
Most if not all drop-outs came much later. The better measure is the 70% SVR ITT measure at 12 weeks for the whole trial. Using 2/3 you 47%. Using 15% (feels more right to me), you get 60%. But I still think 12 + 24 SOC (12 being concurrently and 12 after stopping) will win out ultimately.

Jon

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