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Post# of 253268
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Jonathan Robinson

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Jonathan Robinson

Re: DewDiligence post# 45072

Sunday, 04/15/2007 10:02:16 PM

Sunday, April 15, 2007 10:02:16 PM

Post# of 253268
Most of the analysis I have seen is using 17 as the denominator - not the 20 number expected to be randomized into Arm D. The 17 are those receiving 1 or more treatments.

The drop rate in Arm D was much higher than in Prove 1 by the way, 4/17 vs. 11% overall.

It also appears there may be some failures with SVRs judging from the response at 12 weeks measured on an ITT-basis vs. LOC-basis. The LOC basis is significantly higher and represents using the last measurement for droppers.

Jon
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