VRTX – Despite the comments in #msg-18686414, I think you are correct in the sense that VRTX will now deemphasize ITT as much as possible. With the early dropout rate in PROVE-1 being as high as it is (even though it is not especially high in an absolute sense), Boger’s Hope as detailed in #msg-11635070 will be mathematically unattainable.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”