>I do not think Boger meant on an ITT basis…<
Having listened to the webcast in which Boger made the comments in question, I’m quiet sure that Boger was referring to the SVR rate on an ITT basis. The ITT number is the number of concern to the FDA, and the question on the webcast was asked in the context of the regulatory strategy for VX-950.
>…it looks like 85% on ITT basis is next to impossible to achieve just because of under-enrollment and misc dropouts…<
In other words, VX-950 is not living up to Boger’s hopes, a point that sell-side analysts are now trying to cover up.
“The efficient-market hypothesis may be
the foremost piece of B.S. ever promulgated
in any area of human knowledge!”