Wednesday, May 27, 2026 6:10:56 AM
A lot of handwaving here.
First, where does the $250K up front number come from? The older number I recall was closer to $55K per year adjusted for inflation. Even $55K times three years is about $165K, not $250K up front, and it still does not show that money is flowing to NWBO.
If patients were paying roughly $250K up front and there were hundreds annually, that should be very visible in NWBO’s financials. Even 100 patients would imply $25M. That kind of revenue should reduce the need for dilution.
Even if the net profit were zero, meaningful compassionate use activity should still leave some footprint: revenue, cost recovery, related expenses, revenue recognition notes, or discussion in the company’s filings.
There is also an operational issue. DCVax-L requires leukapheresis to start the process. If NWBO only recently brought the leukapheresis clinic online, that does not fit well with the idea that hundreds of compassionate use patients were already being handled annually.
So either the compassionate use numbers are not that large, the money is not flowing to NWBO, the activity is handled elsewhere, or your theory has a few holes in it.
The rest looks like wishful thinking. Pancreatic patients, broader labels, tumor agnostic approval, ASCO booth language, EDEN timing, off label use, and insurance coverage are all being stacked into one optimistic story without much to back it up.
Can you point to any PRs, 8-Ks, or filings that support this? Otherwise, all this seems very unlikely.
First, where does the $250K up front number come from? The older number I recall was closer to $55K per year adjusted for inflation. Even $55K times three years is about $165K, not $250K up front, and it still does not show that money is flowing to NWBO.
If patients were paying roughly $250K up front and there were hundreds annually, that should be very visible in NWBO’s financials. Even 100 patients would imply $25M. That kind of revenue should reduce the need for dilution.
Even if the net profit were zero, meaningful compassionate use activity should still leave some footprint: revenue, cost recovery, related expenses, revenue recognition notes, or discussion in the company’s filings.
There is also an operational issue. DCVax-L requires leukapheresis to start the process. If NWBO only recently brought the leukapheresis clinic online, that does not fit well with the idea that hundreds of compassionate use patients were already being handled annually.
So either the compassionate use numbers are not that large, the money is not flowing to NWBO, the activity is handled elsewhere, or your theory has a few holes in it.
The rest looks like wishful thinking. Pancreatic patients, broader labels, tumor agnostic approval, ASCO booth language, EDEN timing, off label use, and insurance coverage are all being stacked into one optimistic story without much to back it up.
Can you point to any PRs, 8-Ks, or filings that support this? Otherwise, all this seems very unlikely.
Recent NWBO News
- How Advanced Drug Delivery Could Improve Existing Cancer Treatments • GlobeNewswire Inc. • 06/01/2026 12:30:00 PM
- CNS Drug Delivery Breakthroughs Unlock Significant Biotech Market Opportunities • InvestorsHub NewsWire • 05/11/2026 01:00:00 PM
- CNS Drug Delivery Breakthroughs Unlock Significant Biotech Market Opportunities • GlobeNewswire Inc. • 05/11/2026 12:30:00 PM
- Northwest Biotherapeutics Appoints Dr. Annalisa Jenkins As Strategic Adviser To Advance Dendritic Cell Cancer Vaccine Platform • PR Newswire (US) • 04/30/2026 04:38:00 PM
- Northwest Biotherapeutics Appoints Dr. Annalisa Jenkins As Strategic Adviser To Advance Dendritic Cell Cancer Vaccine Platform • PR Newswire (US) • 04/30/2026 04:30:00 PM
- Northwest Biotherapeutics Announces Establishment Of the Company's Own Dedicated Leukapheresis Clinic • PR Newswire (US) • 04/21/2026 01:30:00 PM
- Northwest Biotherapeutics Announces Establishment Of the Company's Own Dedicated Leukapheresis Clinic • PR Newswire (US) • 04/21/2026 01:30:00 PM
- Form EFFECT - Notice of Effectiveness • Edgar (US Regulatory) • 04/21/2026 04:15:08 AM
- Form POS AM - Post-Effective amendments for registration statement • Edgar (US Regulatory) • 04/16/2026 09:25:30 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 04/07/2026 04:30:50 PM
- Form NT 10-K - Notification of inability to timely file Form 10-K 405, 10-K, 10-KSB 405, 10-KSB, 10-KT, or 10-KT405 • Edgar (US Regulatory) • 03/31/2026 09:04:37 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/15/2026 10:06:20 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/02/2026 10:14:59 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 11/28/2025 09:43:27 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 11/25/2025 10:23:07 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/20/2025 09:26:03 PM
- Form PRE 14A - Other preliminary proxy statements • Edgar (US Regulatory) • 11/19/2025 09:15:48 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/14/2025 09:44:21 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/31/2025 04:29:10 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/30/2025 08:40:05 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/24/2025 04:28:38 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/14/2025 06:22:26 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/14/2025 09:00:38 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 07/01/2025 09:04:38 PM
