Beartrap, remember in at least the UK hub and spoke production will be utilized, I gather there are many sites which are suitable to be spokes. If the new secondary cleanroom is less profitable for NWBO than spoke activities, I'm unsure it they'll need that facility. You're probably right that they'll keep it, but we really have no idea what it's capability is at this point.
The cleanroom they were originally going to build in Sawston wasn't to be that big, I believe it was only intended to handle 20 to 40 EDEN's, the one they'll be contracting with may only have roughly that much capacity. As I remember the plan for the original structure at Sawston, I believe two large cleanrooms were to go above the existing structure when it is completely built out. I would suspect that when the new Sawston facility is built, then the two new cleanrooms above the existing structure, and you add the spoke activities, I think they'll have all the capacity they'll need for Europe at least until many other cancers are routinely being treated. If all of Europe agrees to the hub and spoke plan, I believe that much production will be possible from many of Europe's hospitals and research institutions.
One of the beauties of the EDEN Unit is the ease of installation and removal. I don't believe the unit adds much heat, so existing air conditioning in the cleanroom should be adequate, nor do I believe it uses that much power. As I gather it, two tube pumps, similar to what's used to pump IV fluids in a hospital, are the key to the unit. If they build the EDEN's similar to the IV pumps they'll have rechargeable batteries in the unit capable of operating for several hours in the event of a power outage. While I believe any cleanrooms should have back-up power, such an arrangement would eliminate a failure in the back-up which could occur. I believe every unit will be monitored by FlaskWorks over the internet, as well as on a computer at the site of the EDEN's. I know this may be an oversimplification but if I'm right, after unpacking and assembling an EDEN it should only need to be powered up, tied to the computer network, have diagnostics run and verified to be operational, and it would be ready for the insertion of a loaded disposable cassette and to begin production of it's first batch of vaccine. Remember, I know nothing about it, and I said this was oversimplified, it's probably far more complex, but if remote diagnostics works properly I don't believe it needs to be very complex.
Gary
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